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Therapeutic applications of chymase inhibitors in cardiovascular diseases and fibrosis  • REVIEW ARTICLE Shinji Takai, Denan Jin, Michiko Muramatsu, Yukiko Okamoto and Mizuo Miyazaki SummaryPlus | Full Text + Links | PDF (246 K) | |||
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Cyclooxygenase inhibition in human monocytes increases endotoxin-induced TNFα without affecting cyclooxygenase-2 expression  • ARTICLE Ruth Ulcar, Bernhard A. Peskar, Rufina Schuligoi, Akos Heinemann, Harald H. Kessler, Brigitte I. Santner and Rainer Amann SummaryPlus | Full Text + Links | PDF (189 K) | |||
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Antitumor effect of avermectins  • ARTICLE Victor A. Drinyaev, Vladimir A. Mosin, Elena B. Kruglyak, Tamara S. Novik, Tatiana S. Sterlina, Natalia V. Ermakova, Ludmila N. Kublik, Maria Kh. Levitman, Vera V. Shaposhnikova and Yuri N. Korystov SummaryPlus | Full Text + Links | PDF (232 K) | |||
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Effect of melatonin on the generation of nitric oxide in murine macrophages  • ARTICLE Shen Zhang, Wei Li, Qiuhua Gao and Taotao Wei SummaryPlus | Full Text + Links | PDF (310 K) | |||
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The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic β-cells  • ARTICLE Paul E. Squires, Claire E. Hills, Gareth J. Rogers, Patrick Garland, Sophia R. Farley and Noel G. Morgan SummaryPlus | Full Text + Links | PDF (514 K) | |||
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Prodelphinidin B-2 3,3′-di-O-gallate from Myrica rubra inhibits proliferation of A549 carcinoma cells via blocking cell cycle progression and inducing apoptosis  • ARTICLE Po-Lin Kuo, Ya-Ling Hsu, Ta-Chen Lin and Chun-Ching Lin SummaryPlus | Full Text + Links | PDF (418 K) | |||
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Functional pharmacology of human prostanoid EP2 and EP4 receptors  • ARTICLE Richard J. Wilson, Sharron A. Rhodes, Richard L. Wood, Vanessa J. Shield, L. Staton Noel, David W. Gray and Heather Giles SummaryPlus | Full Text + Links | PDF (381 K) | |||
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Comparative pharmacology of bovine, human and rat vasopressin receptor isoforms  • ARTICLE Miriam Andrés, Ana Peña, Sylvain Derick, Danièle Raufaste, Jerzy Trojnar, Kazimierz Wisniewski, Miguel Trueba, Claudine Serradeil-Le Gal and Gilles Guillon SummaryPlus | Full Text + Links | PDF (484 K) | |||
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Toosendanin, a triterpenoid derivative, acts as a novel agonist of L-type Ca2+ channels in neonatal rat ventricular cells  • ARTICLE Mu-Feng Li and Yu-Liang Shi SummaryPlus | Full Text + Links | PDF (521 K) | |||
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Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues  • ARTICLE Zdenĕk Zídek, Eva Kmoníčková and Antonín Holý SummaryPlus | Full Text + Links | PDF (417 K) | |||
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Endothelins induce ETB receptor-mediated mechanical hypernociception in rat hindpaw: roles of cAMP and protein kinase C  • ARTICLE Joice M. da Cunha, Giles A. Rae, Sérgio H. Ferreira and Fernando de Q. Cunha SummaryPlus | Full Text + Links | PDF (271 K) | |||
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Clonidine and guanfacine-induced antinociception in visceral pain: possible role of α2/I2 binding sites  • ARTICLE Masoumeh Sabetkasaie, Setareh Vala, Niaz Khansefid, Ali-Reza Hosseini and Mohammad-Ali Raies Sadat Ladgevardi SummaryPlus | Full Text + Links | PDF (300 K) | |||
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Long-term exposure of rats to tramadol alters brain dopamine and α1-adrenoceptor function that may be related to antidepressant potency  • ARTICLE Agata Faron-Górecka, Maciej Kuœmider, Salim Yalcin Inan, Joanna Siwanowicz, Teresa Piwowarczyk and Marta Dziedzicka-Wasylewska SummaryPlus | Full Text + Links | PDF (425 K) | |||
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Pharmacological properties of JDTic: a novel κ-opioid receptor antagonist  • ARTICLE Ivy Carroll, James B. Thomas, Linda A. Dykstra, Arthur L. Granger, Richard M. Allen, James L. Howard, Gerald T. Pollard, Mario D. Aceto and Louis S. Harris SummaryPlus | Full Text + Links | PDF (264 K) | |||
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Anxiolytic-like activity of MGS0039, a potent group II metabotropic glutamate receptor antagonist, in a marble-burying behavior test  • SHORT COMMUNICATION Toshiharu Shimazaki, Michihiko Iijima and Shigeyuki Chaki SummaryPlus | Full Text + Links | PDF (204 K) | |||
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Arachidonic acid relaxes human pulmonary arteries through K+ channels and nitric oxide pathways  • ARTICLE Pascal Guerard, Françoise Goirand, Nicolas Fichet, Alain Bernard, Luc Rochette, Esteban J. Morcillo, Monique Dumas and Marc Bardou SummaryPlus | Full Text + Links | PDF (776 K) | |||
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A gastrointestinal lipase inhibitor reduces progression of atherosclerosis in mice fed a western-type diet  • ARTICLE Koji Ueshima, Hitomi Akihisa-Umeno, Akira Nagayoshi, Shoji Takakura, Masahiko Matsuo and Seitaro Mutoh SummaryPlus | Full Text + Links | PDF (217 K) | |||
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Effect of cyclohexenonic long-chain fatty alcohol on rat overactive bladder induced by bladder neck obstruction  • ARTICLE Motoaki Saito, Hiroto Suzuki, Masashi Yamada, Katsuya Hikita, Naoto Kobayashi, Yukako Kinoshita, Daisuke Houri, Ikuo Miyagawa and Keisuke Satoh SummaryPlus | Full Text + Links | PDF (510 K) | |||
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Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats  • ARTICLE Akemi Shimizu, Mika Miyoshi, Masami Sugie, Jun Ueyama, Takuji Yamaguchi, Toshinobu Sasaki, Kenzo Takagi, Mingji Jin, Ken-ichi Miyamoto, Akira Tsuji and Takaaki Hasegawa SummaryPlus | Full Text + Links | PDF (282 K) | |||
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Acute relaxation of mouse duodenun by estrogens: Evidence for an estrogen receptor-independent modulation of muscle excitability  • ARTICLE Mario Díaz, Cristina M. Ramírez, Raquel Marin, Jorge Marrero-Alonso, Tomás Gómez and Rafael Alonso SummaryPlus | Full Text + Links | PDF (605 K) | |||
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The bronchodilators 8-iso-prostaglandin E2 and prostaglandin E2 induce K+ current suppression via thromboxane A2 receptors in porcine tracheal smooth muscle  • ARTICLE Peter B. Helli, Adriana Catalli and Luke J. Janssen SummaryPlus | Full Text + Links | PDF (158 K) | |||
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Reduced renal ClC-5 Cl− channel expression in spontaneously hypertensive rats with microalbuminuria  • SHORT COMMUNICATION Karo Tanaka and Toshio Nakaki SummaryPlus | Full Text + Links | PDF (273 K) | |||
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Enhanced ecto-apyrase activity of stimulated endothelial or mesangial cells is downregulated by glucocorticoids in vitro  • ARTICLE Jola J. Kapojos, Anke van den Berg, Theo Borghuis, Bernhard Banas, Sippie Huitema, Klaas Poelstra and Winston W. Bakker SummaryPlus | Full Text + Links | PDF (347 K) | |||
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Anti-inflammatory drugs and tumor necrosis factor-α production from monocytes: role of transcription factor NF-κB and implication for rheumatoid arthritis therapy  • ARTICLE Luisa Lavagno, Gabriele Gunella, Claudio Bardelli, Simona Spina, Luigia Grazia Fresu, Ilario Viano and Sandra Brunelleschi SummaryPlus | Full Text + Links | PDF (339 K) | |||
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Involvement of guanylate cyclase and potassium channels on the delayed phase of mouse carrageenan-induced paw oedema  • ARTICLE Daniel Fernandes and Jamil Assreuy SummaryPlus | Full Text + Links | PDF (213 K) | |||
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Cyclosporine and bromocriptine-induced suppressions of CYP3A1/2 and CYP2C11 are not mediated by prolactin  • ARTICLE Shirley K. Lu, Shellie M. Callahan, Runyan Jin and Lane J. Brunner SummaryPlus | Full Text + Links | PDF (553 K) | |||
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Hepatic glucagon receptor binding and glucose-lowering in vivo by peptidyl and non-peptidyl glucagon receptor antagonists  • ARTICLE Qing Dallas-Yang, Xiaolan Shen, Mathias Strowski, Edward Brady, Richard Saperstein, Raymond E. Gibson, Deborah Szalkowski, Sajjad A. Qureshi, Mari Rios Candelore, Judith E. Fenyk-Melody et al. SummaryPlus | Full Text + Links | PDF (598 K) | |||
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Cannabinoid receptor antagonist reduces heroin self-administration only in dependent rats  • SHORT COMMUNICATION Miguel Navarro, M. Rocio A. Carrera, Ignacio del Arco, Jose Manuel Trigo, George F. Koob and Fernando Rodríguez de Fonseca SummaryPlus | Full Text + Links | PDF (132 K) | |||
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Author index  • INDEX PDF (57 K) | |||
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Keyword index  • INDEX PDF (73 K) | |||
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Editorial Board  • EDITORIAL BOARD PDF (19 K) | |||
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